Rebecca Ann Sosa

Title(s)HS Assistant Clinical Professor, Pathology and Laboratory Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spatial multiomics of arterial regions from cardiac allograft vasculopathy rejected grafts reveal novel insights into the pathogenesis of chronic antibody-mediated rejection. Am J Transplant. 2024 Jan 12. Nevarez-Mejia J, Pickering H, Sosa RA, Valenzuela NM, Fishbein GA, Baldwin WM, Fairchild RL, Reed EF. PMID: 38219867.
      View in: PubMed   Mentions:    Fields:    
    2. Myeloid spatial and transcriptional molecular signature of ischemia-reperfusion injury in human liver transplantation. Hepatol Commun. 2024 Jan 01; 8(1). Sosa RA, Ahn R, Li F, Terry AQ, Qian Z, Bhat A, Sen S, Naini BV, Ito T, Kaldas FM, Hoffmann A, Busuttil RW, Kupiec-Weglinski JW, Gjertson DW, Reed EF. PMID: 38206205; PMCID: PMC10786592.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Human leukocyte antigen class I antibody-activated endothelium promotes CD206+ M2 macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy. Am J Transplant. 2023 Oct 29. Nevarez-Mejia J, Jin YP, Pickering H, Parmar R, Valenzuela NM, Sosa RA, Heidt S, Fishbein GA, Rozengurt E, Baldwin WM, Fairchild RL, Reed EF. PMID: 38379280.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Immune Features of Disparate Liver Transplant Outcomes in Female Hispanics With Nonalcoholic Steatohepatitis. Transplant Direct. 2023 Nov; 9(11):e1550. Sosa RA, Terry AQ, Ito T, Naini BV, Zheng Y, Pickering H, Nevarez-Mejia J, Busuttil RW, Gjertson DW, Kupiec-Weglinski JW, Reed EF, Kaldas FM. PMID: 37876917; PMCID: PMC10593264.
      View in: PubMed   Mentions:
    5. Assessing the role of phosphorylated S6 ribosomal protein in the pathological diagnosis of pulmonary antibody-mediated rejection. J Heart Lung Transplant. 2024 Mar; 43(3):403-413. Lunardi F, Vedovelli L, Pezzuto F, Le Pavec J, Dorfmuller P, Ivanovic M, Pena T, Wassilew K, Perch M, Hirschi S, Chenard MP, Sosa RA, Goddard M, Neil D, Montero-Fernandez A, Rice A, Cozzi E, Rea F, Levine DJ, Roux A, Fishbein GA, Calabrese F. PMID: 37806601.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Virtual Crossmatch: By Any Other Name. Transplantation. 2023 Oct 01; 107(10):e274. Locke AF, Hickey M, Valenzuela NM, Butler C, Sosa R, Zheng Y, Gjertson D, Reed EF, Zhang Q. PMID: 37749817.
      View in: PubMed   Mentions:    Fields:    
    7. Disulfide-HMGB1 signals through TLR4 and TLR9 to induce inflammatory macrophages capable of innate-adaptive crosstalk in human liver transplantation. Am J Transplant. 2023 Dec; 23(12):1858-1871. Terry AQ, Kojima H, Sosa RA, Kaldas FM, Chin JL, Zheng Y, Naini BV, Noguchi D, Nevarez-Mejia J, Jin YP, Busuttil RW, Meyer AS, Gjertson DW, Kupiec-Weglinski JW, Reed EF. PMID: 37567451.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Virtual and Reality: An Analysis of the UCLA Virtual Crossmatch Exchanges. Transplantation. 2023 08 01; 107(8):1776-1785. Locke AF, Hickey M, Valenzuela NM, Butler C, Sosa R, Zheng Y, Gjertson D, Reed EF, Zhang Q. PMID: 36944607; PMCID: PMC10358445.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Cross-Talk between HLA Class I and TLR4 Mediates P-Selectin Surface Expression and Monocyte Capture to Human Endothelial Cells. J Immunol. 2022 10 01; 209(7):1359-1369. Jin YP, Nevarez-Mejia J, Terry AQ, Sosa RA, Heidt S, Valenzuela NM, Rozengurt E, Reed EF. PMID: 36165200; PMCID: PMC9635437.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    10. Apheresis of Deceased Donors as a New Source of Mobilized Peripheral Blood Hematopoietic Stem Cells for Transplant Tolerance. Transplantation. 2023 02 01; 107(2):504-510. Sosa RA, Mone T, Naini BV, Kohn DB, Reed EF, Wheeler K, Campo-Fernandez B, Davila A, Chaffin DJ, DiNorcia J, Kaldas FM, Cohen A, Lum EL, Veale JL, Kogut NM. PMID: 35974436; PMCID: PMC9877104.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Ischemia-reperfusion Injury in Allogeneic Liver Transplantation: A Role of CD4 T Cells in Early Allograft Injury. Transplantation. 2021 09 01; 105(9):1989-1997. Kageyama S, Kadono K, Hirao H, Nakamura K, Ito T, Gjertson DW, Sosa RA, Reed EF, Kaldas FM, Busuttil RW, Kupiec-Weglinski JW, Zhai Y. PMID: 33065722; PMCID: PMC8046839.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    12. T-Cell Immunoglobulin and Mucin Domain-Containing Protein-4 Is Critical for Kupffer Cell Homeostatic Function in the Activation and Resolution of Liver Ischemia Reperfusion Injury. Hepatology. 2021 10; 74(4):2118-2132. Ni M, Zhang J, Sosa R, Zhang H, Wang H, Jin D, Crowley K, Naini B, Reed FE, Busuttil RW, Kupiec-Weglinski JW, Wang X, Zhai Y. PMID: 33999437; PMCID: PMC9060306.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    13. Phosphorylated S6 ribosomal protein expression by immunohistochemistry correlates with de novo donor-specific HLA antibodies in lung allograft recipients. J Heart Lung Transplant. 2021 10; 40(10):1164-1171. Cone BD, Zhang JQ, Sosa RA, Calabrese F, Reed EF, Fishbein GA. PMID: 34330604.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Disulfide High-Mobility Group Box 1 Drives Ischemia-Reperfusion Injury in Human Liver Transplantation. Hepatology. 2021 03; 73(3):1158-1175. Sosa RA, Terry AQ, Kaldas FM, Jin YP, Rossetti M, Ito T, Li F, Ahn RS, Naini BV, Groysberg VM, Zheng Y, Aziz A, Nevarez-Mejia J, Zarrinpar A, Busuttil RW, Gjertson DW, Kupiec-Weglinski JW, Reed EF. PMID: 32426849; PMCID: PMC8722704.
      View in: PubMed   Mentions: 19     Fields:    
    15. Antibody-induced vascular inflammation skews infiltrating macrophages to a novel remodeling phenotype in a model of transplant rejection. Am J Transplant. 2020 10; 20(10):2686-2702. Wei X, Valenzuela NM, Rossetti M, Sosa RA, Nevarez-Mejia J, Fishbein GA, Mulder A, Dhar J, Keslar KS, Baldwin WM, Fairchild RL, Hou J, Reed EF. PMID: 32320528; PMCID: PMC7529968.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury. J Clin Invest. 2020 05 01; 130(5):2689-2704. Nakamura K, Kageyama S, Kaldas FM, Hirao H, Ito T, Kadono K, Dery KJ, Kojima H, Gjertson DW, Sosa RA, Kujawski M, Busuttil RW, Reed EF, Kupiec-Weglinski JW. PMID: 32027621; PMCID: PMC7190917.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    17. Pattern Recognition Receptor-reactivity Screening of Liver Transplant Patients: Potential for Personalized and Precise Organ Matching to Reduce Risks of Ischemia-reperfusion Injury. Ann Surg. 2020 05; 271(5):922-931. Sosa RA, Rossetti M, Naini BV, Groysberg VM, Kaldas FM, Busuttil RW, Chang YL, Gjertson DW, Kupiec-Weglinski JW, Reed EF. PMID: 30480558; PMCID: PMC6620163.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    18. Recipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside. Am J Transplant. 2019 02; 19(2):356-367. Kageyama S, Hirao H, Nakamura K, Ke B, Zhang M, Ito T, Aziz A, Oncel D, Kaldas FM, Busuttil RW, Sosa RA, Reed EF, Araujo JA, Kupiec-Weglinski JW. PMID: 30059195; PMCID: PMC6349504.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    19. Recombinant relaxin protects liver transplants from ischemia damage by hepatocyte glucocorticoid receptor: From bench-to-bedside. Hepatology. 2018 07; 68(1):258-273. Kageyama S, Nakamura K, Fujii T, Ke B, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. PMID: 29350771; PMCID: PMC6033647.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    20. Heme oxygenase-1 regulates sirtuin-1-autophagy pathway in liver transplantation: From mouse to human. Am J Transplant. 2018 05; 18(5):1110-1121. Nakamura K, Kageyama S, Yue S, Huang J, Fujii T, Ke B, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. PMID: 29136322; PMCID: PMC5910267.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    21. Outside-in HLA class I signaling regulates ICAM-1 clustering and endothelial cell-monocyte interactions via mTOR in transplant antibody-mediated rejection. Am J Transplant. 2018 05; 18(5):1096-1109. Salehi S, Sosa RA, Jin YP, Kageyama S, Fishbein MC, Rozengurt E, Kupiec-Weglinski JW, Reed EF. PMID: 29045076; PMCID: PMC5904014.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    22. Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human. Liver Transpl. 2017 10; 23(10):1282-1293. Nakamura K, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. PMID: 28719070; PMCID: PMC5705033.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    23. Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury. J Hepatol. 2017 12; 67(6):1232-1242. Nakamura K, Zhang M, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Araujo JA, Kupiec-Weglinski JW. PMID: 28842295; PMCID: PMC5884687.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    24. Early cytokine signatures of ischemia/reperfusion injury in human orthotopic liver transplantation. JCI Insight. 2016 12 08; 1(20):e89679. Sosa RA, Zarrinpar A, Rossetti M, Lassman CR, Naini BV, Datta N, Rao P, Harre N, Zheng Y, Spreafico R, Hoffmann A, Busuttil RW, Gjertson DW, Zhai Y, Kupiec-Weglinski JW, Reed EF. PMID: 27942590; PMCID: PMC5135282.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    25. IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation. Proc Natl Acad Sci U S A. 2015 Sep 08; 112(36):E5038-47. Sosa RA, Murphey C, Robinson RR, Forsthuber TG. PMID: 26305941; PMCID: PMC4568689.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    26. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15; 191(12):5848-57. Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. PMID: 24227784; PMCID: PMC3891847.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCellsPHPublic Health
    27. The critical role of antigen-presentation-induced cytokine crosstalk in the central nervous system in multiple sclerosis and experimental autoimmune encephalomyelitis. J Interferon Cytokine Res. 2011 Oct; 31(10):753-68. Sosa RA, Forsthuber TG. PMID: 21919736; PMCID: PMC3189551.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    28. More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases. Immunotherapy. 2011 Mar; 3(3):435-41. Ji N, Sosa RA, Forsthuber TG. PMID: 21395384; PMCID: PMC3160828.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
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