Andrew C Charles

Title(s)Professor, Neurology
SchoolMedicine
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    Dr. Andrew C. Charles holds the Meyer and Renee Luskin Chair in Migraine and Headache Studies.

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    MECHANISMS AND FUNCTIONS OF ASTROCYTE CALCIUM SIGNALING
    NIH R01NS039961Sep 30, 2000 - Aug 31, 2007
    Role: Principal Investigator
    GLIAL CELL SIGNALING IN CENTRAL NERVOUS SYSTEM INJURY
    NIH R29NS032283Aug 15, 1995 - Jul 31, 2001
    Role: Principal Investigator

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    Collapse Clinical Trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Efficacy and Safety of Eptinezumab in Episodic Cluster Headache: A Randomized Clinical Trial. JAMA Neurol. 2025 May 19. Jensen RH, Tassorelli C, Tepper SJ, Charles A, Goadsby PJ, Snoer AH, Sperling B, Krog Josiassen M, Borgen Linander C, Ettrup A, Boneva N. PMID: 40388178; PMCID: PMC12090066.
      View in: PubMed   Mentions:    Fields:    
    2. Long-term safety, tolerability, and efficacy of eptinezumab in chronic cluster headache (CHRONICLE): an open-label safety trial. Lancet Neurol. 2025 May; 24(5):429-440. Tassorelli C, Jensen RH, Goadsby PJ, Charles AC, Tepper SJ, Snoer AH, Josiassen MK, Linander CB, Ettrup A, Sperling B, Boneva N. PMID: 40252664.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. The cortical spreading depression/migraine aura hypothesis - Finally some definitive evidence. Headache. 2025 Apr; 65(4):537-538. Charles AC, Goadsby PJ. PMID: 40105144.
      View in: PubMed   Mentions:    Fields:    
    4. The headache research priorities: Research goals from the American Headache Society and an international multistakeholder expert group. Headache. 2024 09; 64(8):912-930. Schwedt TJ, Pradhan AA, Oshinsky ML, Brin MF, Rosen H, Lalvani N, Charles A, Ashina M, Do TP, Burstein R, Gelfand AA, Dodick DW, Pozo-Rosich P, Lipton RB, Ailani J, Szperka CL, Charleston L, Digre KB, Russo AF, Buse DC, Powers SW, Tassorelli C, Goadsby PJ, Headache Research Priorities Working Group Members. PMID: 39149968.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    5. Calcitonin gene-related peptide-targeting therapies are a first-line option for the prevention of migraine: An American Headache Society position statement update. Headache. 2024 04; 64(4):333-341. Charles AC, Digre KB, Goadsby PJ, Robbins MS, Hershey A, American Headache Society. PMID: 38466028.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    6. The role of caffeine in headache disorders. Curr Opin Neurol. 2024 06 01; 37(3):289-294. Charles A. PMID: 38327229.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Reduction in retinal microvascular perfusion during migraine attacks. Headache. 2024 01; 64(1):16-36. Podraza K, Bangera N, Feliz A, Charles A. PMID: 38031892.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Effects of chronic caffeine on patterns of brain blood flow and behavior throughout the sleep-wake cycle in freely behaving mice. PNAS Nexus. 2023 Sep; 2(9):pgad303. Aframian K, Yousef Yengej D, Nwaobi S, Raman S, Faas GC, Charles A. PMID: 37780231; PMCID: PMC10538474.
      View in: PubMed   Mentions: 3  
    9. Aura is a symptom of a migraine attack, not its cause. Headache. 2023 09; 63(8):1029-1030. Charles A. PMID: 37665161.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Pain Following Endoscopic Foreheadplasty Surgery in Women. Aesthet Surg J. 2022 06 20; 42(7):713-721. Lassegard JC, Dubin BJ, Compton P, Charles AC, Macey PM. PMID: 34893790.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Different characteristics of cortical spreading depression in the sleep and wake states. Headache. 2022 05; 62(5):577-587. Yousef Yengej D, Nwaobi SE, Ferando I, Kechechyan G, Charles A, Faas GC. PMID: 35467010.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    12. Ultrasound stimulation of the motor cortex during tonic muscle contraction. PLoS One. 2022; 17(4):e0267268. Heimbuch IS, Fan TK, Wu AD, Faas GC, Charles AC, Iacoboni M. PMID: 35442956; PMCID: PMC9020726.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Migraine. Nat Rev Dis Primers. 2022 01 13; 8(1):2. Ferrari MD, Goadsby PJ, Burstein R, Kurth T, Ayata C, Charles A, Ashina M, van den Maagdenberg AMJM, Dodick DW. PMID: 35027572.
      View in: PubMed   Mentions: 141     Fields:    Translation:Humans
    14. Inflammation in migraine…or not…: A critical evaluation of the evidence. Headache. 2021 Nov; 61(10):1575-1578. Charles A, Nwaobi SE, Goadsby P. PMID: 34806166.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. Continuous long-term recording and triggering of brain neurovascular activity and behaviour in freely moving rodents. J Physiol. 2021 10; 599(20):4545-4559. Yousef Yengej DN, Ferando I, Kechechyan G, Nwaobi SE, Raman S, Charles A, Faas GC. PMID: 34438476.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    16. Memantine for migraine-Big promise but little evidence. Headache. 2021 09; 61(8):1151-1152. Charles A. PMID: 34510445.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Evaluation of Posttraumatic Headache Phenotype and Recovery Time After Youth Concussion. JAMA Netw Open. 2021 03 01; 4(3):e211312. Kamins J, Richards R, Barney BJ, Locandro C, Pacchia CF, Charles AC, Cook LJ, Gioia G, Giza CC, Blume HK. PMID: 33683335; PMCID: PMC7941198.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    18. Pooled Analysis of PFO Occluder Device Trials in Patients With PFO and Migraine. J Am Coll Cardiol. 2021 Feb 16; 77(6):667-676. Mojadidi MK, Kumar P, Mahmoud AN, Elgendy IY, Shapiro H, West B, Charles AC, Mattle HP, Sorensen S, Meier B, Silberstein SD, Tobis JM. PMID: 33573735.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    19. Targeting calcitonin gene-related peptide: a new era in migraine therapy. Lancet. 2019 11 09; 394(10210):1765-1774. Charles A, Pozo-Rosich P. PMID: 31668411.
      View in: PubMed   Mentions: 110     Fields:    Translation:Humans
    20. Differences in treatment response between migraine with aura and migraine without aura: lessons from clinical practice and RCTs. J Headache Pain. 2019 Sep 06; 20(1):96. Hansen JM, Charles A. PMID: 31492106; PMCID: PMC6734209.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    21. Advanced Imaging in the Evaluation of Migraine Headaches. Neuroimaging Clin N Am. 2019 May; 29(2):301-324. Ellingson BM, Hesterman C, Johnston M, Dudeck NR, Charles AC, Villablanca JP. PMID: 30926119; PMCID: PMC8765285.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    22. A new opportunity after migraine treatment failure? Lancet. 2018 11 24; 392(10161):2241-2242. Charles A. PMID: 30360967.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. The Migraine Aura. Continuum (Minneap Minn). 2018 08; 24(4, Headache):1009-1022. Charles A. PMID: 30074546.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    24. Posttraumatic Headache: Basic Mechanisms and Therapeutic Targets. Headache. 2018 Jun; 58(6):811-826. Kamins J, Charles A. PMID: 29757458.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    25. Cortical spreading depression as a site of origin for migraine: Role of CGRP. Cephalalgia. 2019 03; 39(3):428-434. Close LN, Eftekhari S, Wang M, Charles AC, Russo AF. PMID: 29695168; PMCID: PMC7007998.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    26. Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke. Stroke. 2018 05; 49(5):1123-1128. West BH, Noureddin N, Mamzhi Y, Low CG, Coluzzi AC, Shih EJ, Gevorgyan Fleming R, Saver JL, Liebeskind DS, Charles A, Tobis JM. PMID: 29636424; PMCID: PMC5915909.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    27. Glutamate and Its Receptors as Therapeutic Targets for Migraine. Neurotherapeutics. 2018 04; 15(2):361-370. Hoffmann J, Charles A. PMID: 29508147; PMCID: PMC5935645.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimals
    28. A multicenter, prospective, single arm, open label, observational study of sTMS for migraine prevention (ESPOUSE Study). Cephalalgia. 2018 05; 38(6):1038-1048. Starling AJ, Tepper SJ, Marmura MJ, Shamim EA, Robbins MS, Hindiyeh N, Charles AC, Goadsby PJ, Lipton RB, Silberstein SD, Gelfand AA, Chiacchierini RP, Dodick DW. PMID: 29504483; PMCID: PMC5944078.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    29. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018 02; 17(2):174-182. Charles A. PMID: 29229375.
      View in: PubMed   Mentions: 217     Fields:    Translation:Humans
    30. Percutaneous Closure of Patent Foramen Ovale in Patients With Migraine: The PREMIUM Trial. J Am Coll Cardiol. 2017 Dec 05; 70(22):2766-2774. Tobis JM, Charles A, Silberstein SD, Sorensen S, Maini B, Horwitz PA, Gurley JC. PMID: 29191325.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    31. Migraine. N Engl J Med. 2017 10 26; 377(17):1698-1699. Charles A. PMID: 29069565.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Foveal and Peripapillary Vascular Decrement in Migraine With Aura Demonstrated by Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. 2017 10 01; 58(12):5477-5484. Chang MY, Phasukkijwatana N, Garrity S, Pineles SL, Rahimi M, Sarraf D, Johnston M, Charles A, Arnold AC. PMID: 29059314; PMCID: PMC5656414.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    33. Migraine. N Engl J Med. 2017 Aug 10; 377(6):553-561. Charles A. PMID: 28792865.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    34. Facial presentations of primary headache disorders. Cephalalgia. 2017 Jun; 37(7):714-719. Sharav Y, Katsarava Z, Charles A. PMID: 28399652.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    35. Peripheral Sensory Neurons Expressing Melanopsin Respond to Light. Front Neural Circuits. 2016; 10:60. Matynia A, Nguyen E, Sun X, Blixt FW, Parikh S, Kessler J, Pérez de Sevilla Müller L, Habib S, Kim P, Wang ZZ, Rodriguez A, Charles A, Nusinowitz S, Edvinsson L, Barnes S, Brecha NC, Gorin MB. PMID: 27559310; PMCID: PMC4978714.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    36. The effects of acute and preventive migraine therapies in a mouse model of chronic migraine. Cephalalgia. 2016 Oct; 36(11):1048-1056. Tipton AF, Tarash I, McGuire B, Charles A, Pradhan AA. PMID: 26682574; PMCID: PMC5557701.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    37. Delta-opioid receptors as targets for migraine therapy. Curr Opin Neurol. 2016 06; 29(3):314-9. Charles A, Pradhan AA. PMID: 27023737.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    38. Comment: Outcomes of migraine therapy with IV dihydroergotamine. Neurology. 2016 Mar 01; 86(9):859. Charles A. PMID: 26843565.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice. J Cereb Blood Flow Metab. 2017 May; 37(5):1641-1655. Houben T, Loonen IC, Baca SM, Schenke M, Meijer JH, Ferrari MD, Terwindt GM, Voskuyl RA, Charles A, van den Maagdenberg AM, Tolner EA. PMID: 27107026; PMCID: PMC5435281.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    40. New therapeutic approaches for the prevention and treatment of migraine. Lancet Neurol. 2015 Oct; 14(10):1010-22. Diener HC, Charles A, Goadsby PJ, Holle D. PMID: 26376968.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    41. Migraine aura: new ideas about cause, classification, and clinical significance. Curr Opin Neurol. 2015 Jun; 28(3):255-60. Charles A, Hansen JM. PMID: 25923125.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    42. Variability of clinical features in attacks of migraine with aura. Cephalalgia. 2016 Mar; 36(3):216-24. Hansen JM, Goadsby PJ, Charles AC. PMID: 25944814.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    43. Reduced efficacy of sumatriptan in migraine with aura vs without aura. Neurology. 2015 May 05; 84(18):1880-5. Hansen JM, Goadsby PJ, Charles A. PMID: 25841032.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    44. Sounding out migraine-related interactions between the brainstem and cortex. Cephalalgia. 2015 Oct; 35(11):941-3. Charles A. PMID: 25616609.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    45. The thalamic reticular nucleus is activated by cortical spreading depression in freely moving rats: prevention by acute valproate administration. Eur J Neurosci. 2015 Jan; 41(1):120-8. Tepe N, Filiz A, Dilekoz E, Akcali D, Sara Y, Charles A, Bolay H. PMID: 25327971.
      View in: PubMed   Mentions: 30  Translation:Animals
    46. Memantine enhances recovery from stroke. Stroke. 2014 Jul; 45(7):2093-2100. López-Valdés HE, Clarkson AN, Ao Y, Charles AC, Carmichael ST, Sofroniew MV, Brennan KC. PMID: 24938836; PMCID: PMC4142682.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    47. δ-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice. Br J Pharmacol. 2014 May; 171(9):2375-84. Pradhan AA, Smith ML, Zyuzin J, Charles A. PMID: 24467301; PMCID: PMC3997277.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    48. Distinctive anatomical and physiological features of migraine aura revealed by 18 years of recording. Brain. 2013 Dec; 136(Pt 12):3589-95. Hansen JM, Baca SM, Vanvalkenburgh P, Charles A. PMID: 24264937.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    49. Characterization of a novel model of chronic migraine. Pain. 2014 Feb; 155(2):269-274. Pradhan AA, Smith ML, McGuire B, Tarash I, Evans CJ, Charles A. PMID: 24121068; PMCID: PMC3920577.
      View in: PubMed   Mentions: 147     Fields:    Translation:Animals
    50. Cortical spreading depression and migraine. Nat Rev Neurol. 2013 Nov; 9(11):637-44. Charles AC, Baca SM. PMID: 24042483.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimals
    51. Pain referral patterns of the C1 to C3 nerves: implications for headache disorders. Ann Neurol. 2013 Jul; 74(1):145-8. Johnston MM, Jordan SE, Charles AC. PMID: 23424170.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    52. Migraine: a brain state. Curr Opin Neurol. 2013 Jun; 26(3):235-9. Charles A. PMID: 23493160.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    53. Casein kinase iδ mutations in familial migraine and advanced sleep phase. Sci Transl Med. 2013 May 01; 5(183):183ra56, 1-11. Brennan KC, Bates EA, Shapiro RE, Zyuzin J, Hallows WC, Huang Y, Lee HY, Jones CR, Fu YH, Charles AC, Ptácek LJ. PMID: 23636092; PMCID: PMC4220792.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    54. Vasodilation out of the picture as a cause of migraine headache. Lancet Neurol. 2013 May; 12(5):419-20. Charles A. PMID: 23578774.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    55. Multimodal examination of structural and functional remapping in the mouse photothrombotic stroke model. J Cereb Blood Flow Metab. 2013 May; 33(5):716-23. Clarkson AN, López-Valdés HE, Overman JJ, Charles AC, Brennan KC, Thomas Carmichael S. PMID: 23385201; PMCID: PMC3652691.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    56. The evolution of a migraine attack - a review of recent evidence. Headache. 2013 Feb; 53(2):413-9. Charles A. PMID: 23278169.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    57. Migraine headache is present in the aura phase: a prospective study. Neurology. 2012 Nov 13; 79(20):2044-9. Hansen JM, Lipton RB, Dodick DW, Silberstein SD, Saper JR, Aurora SK, Goadsby PJ, Charles A. PMID: 23115208; PMCID: PMC3511920.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    58. Spontaneous behavioral responses in the orofacial region: a model of trigeminal pain in mouse. Headache. 2013 Jan; 53(1):137-151. Romero-Reyes M, Akerman S, Nguyen E, Vijjeswarapu A, Hom B, Dong HW, Charles AC. PMID: 22830495; PMCID: PMC3664930.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    59. Migraine is not primarily a vascular disorder. Cephalalgia. 2012 Apr; 32(5):431-2. Charles A. PMID: 22523235.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    60. Defining and refining 5-HT receptor targets for migraine. Lancet Neurol. 2012 May; 11(5):383-4. Charles A. PMID: 22459548.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    61. [Novel migraine mechanisms as targets for therapy]. Rinsho Shinkeigaku. 2012; 52(11):900. Charles A. PMID: 23196458.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    62. Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells. Leuk Lymphoma. 2011 Nov; 52(11):2169-78. Rodríguez JA, Luria-Pérez R, López-Valdés HE, Casero D, Daniels TR, Patel S, Avila D, Leuchter R, So S, Ortiz-Sánchez E, Bonavida B, Martínez-Maza O, Charles AC, Pellegrini M, Helguera G, Penichet ML. PMID: 21870996; PMCID: PMC3732792.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    63. Headache: new genes, new mechanisms, and new therapies. Lancet Neurol. 2011 Jan; 10(1):13-4. Charles A. PMID: 21163439.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Bradykinin increases resensitization of purinergic receptor signaling in glioma cells. Cancer Cell Int. 2010 Sep 27; 10:35. López-Valdés HE, Beltran-Parrazal L, Brennan KC, Charles AC. PMID: 20875097; PMCID: PMC2955562.
      View in: PubMed   Mentions: 2  
    65. An update on the blood vessel in migraine. Curr Opin Neurol. 2010 Jun; 23(3):266-74. Brennan KC, Charles A. PMID: 20216215; PMCID: PMC5500293.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    66. Does cortical spreading depression initiate a migraine attack? Maybe not . . . Headache. 2010 Apr; 50(4):731-3. Charles A. PMID: 20456161.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    67. Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression. Brain. 2010 Apr; 133(Pt 4):996-1012. Chang JC, Shook LL, Biag J, Nguyen EN, Toga AW, Charles AC, Brennan KC. PMID: 20348134; PMCID: PMC2850576.
      View in: PubMed   Mentions: 67     Fields:    Translation:Animals
    68. Stimulating studies of visual cortical function in migraine. Cephalalgia. 2010 Jun; 30(6):643-5. Charles A. PMID: 20511203.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. The neurobiology of migraine. Handb Clin Neurol. 2010; 97:99-108. Charles A, Brennan KC. PMID: 20816413; PMCID: PMC5494713.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    70. Gliopathic pain: when satellite glial cells go bad. Neuroscientist. 2009 Oct; 15(5):450-63. Ohara PT, Vit JP, Bhargava A, Romero M, Sundberg C, Charles AC, Jasmin L. PMID: 19826169; PMCID: PMC2852320.
      View in: PubMed   Mentions: 77     Fields:    
    71. Cortical spreading depression-new insights and persistent questions. Cephalalgia. 2009 Oct; 29(10):1115-24. Charles A, Brennan K. PMID: 19735537; PMCID: PMC5500297.
      View in: PubMed   Mentions: 75     Fields:    
    72. Sleep and headache. Semin Neurol. 2009 Sep; 29(4):406-18. Brennan KC, Charles A. PMID: 19742415; PMCID: PMC5605773.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    73. Advances in the basic and clinical science of migraine. Ann Neurol. 2009 May; 65(5):491-8. Charles A. PMID: 19479724.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    74. Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS. Dis Model Mech. 2009 Mar-Apr; 2(3-4):189-95. Karumbayaram S, Kelly TK, Paucar AA, Roe AJ, Umbach JA, Charles A, Goldman SA, Kornblum HI, Wiedau-Pazos M. PMID: 19259395; PMCID: PMC2650191.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    75. The neurogenic basis of migraine. Headache. 2008 Oct; 48(9):1411-4. Cutrer FM, Charles A. PMID: 19006559.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    76. A touch of increased pain: cutaneous allodynia in migraine. Ann Neurol. 2008 Feb; 63(2):130-2. Charles A, Brennan KC. PMID: 18306413.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. Memantine for prevention of migraine: a retrospective study of 60 cases. J Headache Pain. 2007 Sep; 8(4):248-50. Charles A, Flippen C, Romero Reyes M, Brennan KC. PMID: 17901918; PMCID: PMC3451671.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    78. Sumatriptan-naproxen combination for acute migraine. Nat Clin Pract Neurol. 2007 Nov; 3(11):604-5. Charles A, Brennan KC. PMID: 17848929.
      View in: PubMed   Mentions:    Fields:    
    79. Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor. J Control Release. 2007 Dec 04; 124(1-2):35-42. Rodríguez JA, Helguera G, Daniels TR, Neacato II, López-Valdés HE, Charles AC, Penichet ML. PMID: 17884229.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    80. Reduced threshold for cortical spreading depression in female mice. Ann Neurol. 2007 Jun; 61(6):603-6. Brennan KC, Romero Reyes M, López Valdés HE, Arnold AP, Charles AC. PMID: 17474110.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    81. Distinct vascular conduction with cortical spreading depression. J Neurophysiol. 2007 Jun; 97(6):4143-51. Brennan KC, Beltrán-Parrazal L, López-Valdés HE, Theriot J, Toga AW, Charles AC. PMID: 17329631.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    82. Genetic program of neuronal differentiation and growth induced by specific activation of NMDA receptors. Neurochem Res. 2007 Feb; 32(2):363-76. Ghiani CA, Beltran-Parrazal L, Sforza DM, Malvar JS, Seksenyan A, Cole R, Smith DJ, Charles A, Ferchmin PA, de Vellis J. PMID: 17191130.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    83. Mitochondrial transport in processes of cortical neurons is independent of intracellular calcium. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1193-7. Beltran-Parrazal L, López-Valdés HE, Brennan KC, Díaz-Muñoz M, de Vellis J, Charles AC. PMID: 16885395.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    84. K+ channel KV3.1 associates with OSP/claudin-11 and regulates oligodendrocyte development. Am J Physiol Cell Physiol. 2006 Oct; 291(4):C687-98. Tiwari-Woodruff S, Beltran-Parrazal L, Charles A, Keck T, Vu T, Bronstein J. PMID: 16624990.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    85. Gene expression is differentially regulated by neurotransmitters in embryonic neuronal cortical culture. J Neurochem. 2006 Apr; 97 Suppl 1:35-43. Ghiani CA, Lelievre V, Beltran-Parrazal L, Sforza DM, Malvar J, Smith DJ, Charles AC, Ferchmin PA, de Vellis J. PMID: 16635248.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    86. Oculodentodigital dysplasia connexin43 mutations result in non-functional connexin hemichannels and gap junctions in C6 glioma cells. J Cell Sci. 2006 Feb 01; 119(Pt 3):532-41. Lai A, Le DN, Paznekas WA, Gifford WD, Jabs EW, Charles AC. PMID: 16418219.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    87. Teaching resources. Glial intercellular waves. Sci STKE. 2005 Jun 28; 2005(290):tr19. Charles A. PMID: 15985642.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    88. Reaching out beyond the synapse: glial intercellular waves coordinate metabolism. Sci STKE. 2005 Feb 08; 2005(270):pe6. Charles A. PMID: 15701894.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    89. From inhibition to excitation: functional effects of interaction between opioid receptors. Life Sci. 2004 Dec 17; 76(5):479-85. Charles AC, Hales TG. PMID: 15556161.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    90. EGF activates intracellular and intercellular calcium signaling by distinct pathways in tumor cells. Cancer Biol Ther. 2004 Dec; 3(12):1243-9. Bryant JA, Finn RS, Slamon DJ, Cloughesy TF, Charles AC. PMID: 15611621.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    91. Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin Cancer Res. 2004 Jun 01; 10(11):3667-77. Zhang Y, Zhang YF, Bryant J, Charles A, Boado RJ, Pardridge WM. PMID: 15173073.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    92. Riluzole inhibits spontaneous Ca2+ signaling in neuroendocrine cells by activation of K+ channels and inhibition of Na+ channels. Br J Pharmacol. 2003 Nov; 140(5):881-8. Beltran-Parrazal L, Charles A. PMID: 14530220; PMCID: PMC1574091.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    93. Modulation of intercellular calcium signaling in astrocytes by extracellular calcium and magnesium. Glia. 2003 Sep; 43(3):265-73. Stout C, Charles A. PMID: 12898705.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    94. Lowering cyclic adenosine-3',5'-monophosphate (cAMP) levels by expression of a cAMP-specific phosphodiesterase decreases intrinsic pulsatile gonadotropin-releasing hormone secretion from GT1 cells. Mol Endocrinol. 2003 Oct; 17(10):1982-90. Yoshida H, Beltran-Parrazal L, Butler P, Conti M, Charles AC, Weiner RI. PMID: 12829807.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    95. Coexpression of delta-opioid receptors with micro receptors in GH3 cells changes the functional response to micro agonists from inhibitory to excitatory. Mol Pharmacol. 2003 Jan; 63(1):89-95. Charles AC, Mostovskaya N, Asas K, Evans CJ, Dankovich ML, Hales TG. PMID: 12488540.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    96. Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels. J Biol Chem. 2002 Mar 22; 277(12):10482-8. Stout CE, Costantin JL, Naus CC, Charles AC. PMID: 11790776.
      View in: PubMed   Mentions: 310     Fields:    Translation:AnimalsCells
    97. cAMP modulates the excitability of immortalized H=hypothalamic (GT1) neurons via a cyclic nucleotide gated channel. Mol Endocrinol. 2001 Jun; 15(6):997-1009. Charles A, Weiner R, Costantin J. PMID: 11376117.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    98. Modulation of Ca(2+) signaling by K(+) channels in a hypothalamic neuronal cell line (GT1-1). J Neurophysiol. 2001 Jan; 85(1):295-304. Costantin JL, Charles AC. PMID: 11152729.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    99. Spontaneous action potentials initiate rhythmic intercellular calcium waves in immortalized hypothalamic (GT1-1) neurons. J Neurophysiol. 1999 Jul; 82(1):429-35. Costantin JL, Charles AC. PMID: 10400969.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    100. L-type Ca2+ channels and K+ channels specifically modulate the frequency and amplitude of spontaneous Ca2+ oscillations and have distinct roles in prolactin release in GH3 cells. J Biol Chem. 1999 Mar 12; 274(11):7508-15. Charles AC, Piros ET, Evans CJ, Hales TG. PMID: 10066818.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    101. Intercellular calcium waves in glia. Glia. 1998 Sep; 24(1):39-49. Charles A. PMID: 9700488.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    102. Spiral intercellular calcium waves in hippocampal slice cultures. J Neurophysiol. 1998 Feb; 79(2):1045-52. Harris-White ME, Zanotti SA, Frautschy SA, Charles AC. PMID: 9463460.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    103. A conditionally immortalized glial cell line that expresses mature myelin proteins and functional GABA(A) receptors. J Neurochem. 1998 Feb; 70(2):483-91. Bronstein JM, Hales TG, Tyndale RF, Charles AC. PMID: 9453541.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    104. Extracellular calcium sensing by glial cells: low extracellular calcium induces intracellular calcium release and intercellular signaling. J Neurochem. 1997 Aug; 69(2):594-602. Zanotti S, Charles A. PMID: 9231716.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    105. Intercellular calcium waves in neurons. Mol Cell Neurosci. 1996 May; 7(5):337-53. Charles AC, Kodali SK, Tyndale RF. PMID: 8812061.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    106. Intercellular calcium waves mediated by diffusion of inositol trisphosphate: a two-dimensional model. Am J Physiol. 1995 Jun; 268(6 Pt 1):C1537-45. Sneyd J, Wetton BT, Charles AC, Sanderson MJ. PMID: 7611375.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    107. Mechanisms of spontaneous calcium oscillations and action potentials in immortalized hypothalamic (GT1-7) neurons. J Neurophysiol. 1995 Jan; 73(1):56-64. Charles AC, Hales TG. PMID: 7714589.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    108. GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GT1-7) neurons. Neuroendocrinology. 1994 Mar; 59(3):297-308. Hales TG, Sanderson MJ, Charles AC. PMID: 8159279.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    109. Glia-neuron intercellular calcium signaling. Dev Neurosci. 1994; 16(3-4):196-206. Charles AC. PMID: 7705224.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    110. A model for the propagation of intercellular calcium waves. Am J Physiol. 1994 Jan; 266(1 Pt 1):C293-302. Sneyd J, Charles AC, Sanderson MJ. PMID: 8304425.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    111. Mechanisms and function of intercellular calcium signaling. Mol Cell Endocrinol. 1994 Jan; 98(2):173-87. Sanderson MJ, Charles AC, Boitano S, Dirksen ER. PMID: 8143927.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    112. Neurotransmitters and cytokines in CNS pathology. Prog Brain Res. 1994; 103:319-30. Mitrovic B, Martin FC, Charles AC, Ignarro LJ, Anton PA, Shanahan F, Merrill JE. PMID: 7533912.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    113. bcl-2 inhibits death of central neural cells induced by multiple agents. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4533-7. Zhong LT, Sarafian T, Kane DJ, Charles AC, Mah SP, Edwards RH, Bredesen DE. PMID: 8506295; PMCID: PMC46546.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    114. Mechanisms of intercellular calcium signaling in glial cells studied with dantrolene and thapsigargin. Glia. 1993 Feb; 7(2):134-45. Charles AC, Dirksen ER, Merrill JE, Sanderson MJ. PMID: 8094375.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    115. Substance P stimulates IL-1 production by astrocytes via intracellular calcium. Brain Res. 1992 Dec 18; 599(1):13-8. Martin FC, Charles AC, Sanderson MJ, Merrill JE. PMID: 1283556.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    116. Intercellular calcium signaling via gap junctions in glioma cells. J Cell Biol. 1992 Jul; 118(1):195-201. Charles AC, Naus CC, Zhu D, Kidder GM, Dirksen ER, Sanderson MJ. PMID: 1320034; PMCID: PMC2289532.
      View in: PubMed   Mentions: 60     Fields:    Translation:Cells
    117. Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate. Neuron. 1991 Jun; 6(6):983-92. Charles AC, Merrill JE, Dirksen ER, Sanderson MJ. PMID: 1675864.
      View in: PubMed   Mentions: 166     Fields:    Translation:AnimalsCells
    118. A 49-year-old man with aseptic meningitis and multiple cranial neuropathies. West J Med. 1991 Mar; 154(3):307-14. Mazziotta JC, Itabashi H, Orfuss C, Charles A, Collins R. PMID: 2028589; PMCID: PMC1002751.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    119. Mechanical stimulation and intercellular communication increases intracellular Ca2+ in epithelial cells. Cell Regul. 1990 Jul; 1(8):585-96. Sanderson MJ, Charles AC, Dirksen ER. PMID: 2078569; PMCID: PMC361598.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
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