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Daniel S Shin

Title(s)Assistant Professor-in-Residence, Medicine
SchoolMedicine
Address555 Westwood Plaza MAILROOM
Los Angeles CA 90024
Phone310-478-3711
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer. J Biol Chem. 2020 Oct 07. Veena MS, Raychaudhuri S, Basak SK, Venkatesan N, Kumar P, Biswas R, Chakrabarti R, Lu J, Su T, Gallagher-Jones M, Morselli M, Fu H, Pellegrini M, Goldstein T, Aladjem MI, Rettig MB, Wilczynski SP, Shin DS, Srivatsan ES. PMID: 33028635.
      View in: PubMed   Mentions:    Fields:    
    2. Conserved Interferon-? Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. 2020 Sep 08. Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, Quist M, Martignier C, Luke JJ, Wolchok JD, Johnson DB, Chmielowski B, Hodi FS, Bhatia S, Sharfman W, Urba WJ, Slingluff CL, Diab A, Haanen JBAG, Algarra SM, Pardoll DM, Anagnostou V, Topalian SL, Velculescu VE, Speiser DE, Kalbasi A, Ribas A. PMID: 32916126.
      View in: PubMed   Mentions:    Fields:    
    3. A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes. Cancer. 2020 Apr 15; 126(8):1668-1682. Basak SK, Bera A, Yoon AJ, Morselli M, Jeong C, Tosevska A, Dong TS, Eklund M, Russ E, Nasser H, Lagishetty V, Guo R, Sajed D, Mudgal S, Mehta P, Avila L, Srivastava M, Faull K, Jacobs J, Pellegrini M, Shin DS, Srivatsan ES, Wang MB. PMID: 32022261.
      View in: PubMed   Mentions:    Fields:    
    4. Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated AKI: A Multicenter Study. J Am Soc Nephrol. 2020 02; 31(2):435-446. Cortazar FB, Kibbelaar ZA, Glezerman IG, Abudayyeh A, Mamlouk O, Motwani SS, Murakami N, Herrmann SM, Manohar S, Shirali AC, Kitchlu A, Shirazian S, Assal A, Vijayan A, Renaghan AD, Ortiz-Melo DI, Rangarajan S, Malik AB, Hogan JJ, Dinh AR, Shin DS, Marrone KA, Mithani Z, Johnson DB, Hosseini A, Uprety D, Sharma S, Gupta S, Reynolds KL, Sise ME, Leaf DE. PMID: 31896554.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    5. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2019 Dec 10; 29(11):3766. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 31825850.
      View in: PubMed   Mentions: 3     Fields:    
    6. Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis. Cell Discov. 2019; 5:62. Palaskas NJ, Garcia JD, Shirazi R, Shin DS, Puig-Saus C, Braas D, Ribas A, Graeber TG. PMID: 31798961.
      View in: PubMed   Mentions:
    7. Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation. J Biol Chem. 2019 05 03; 294(18):7245-7258. Aluri S, Zhao R, Lin K, Shin DS, Fiser A, Goldman ID. PMID: 30858177.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Genetic Mechanisms of Immune Evasion in Colorectal Cancer. Cancer Discov. 2018 06; 8(6):730-749. Grasso CS, Giannakis M, Wells DK, Hamada T, Mu XJ, Quist M, Nowak JA, Nishihara R, Qian ZR, Inamura K, Morikawa T, Nosho K, Abril-Rodriguez G, Connolly C, Escuin-Ordinas H, Geybels MS, Grady WM, Hsu L, Hu-Lieskovan S, Huyghe JR, Kim YJ, Krystofinski P, Leiserson MDM, Montoya DJ, Nadel BB, Pellegrini M, Pritchard CC, Puig-Saus C, Quist EH, Raphael BJ, Salipante SJ, Shin DS, Shinbrot E, Shirts B, Shukla S, Stanford JL, Sun W, Tsoi J, Upfill-Brown A, Wheeler DA, Wu CJ, Yu M, Zaidi SH, Zaretsky JM, Gabriel SB, Lander ES, Garraway LA, Hudson TJ, Fuchs CS, Ribas A, Ogino S, Peters U. PMID: 29510987.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    9. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2017 05 09; 19(6):1189-1201. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 28494868.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansCells
    10. Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations. Cancer Discov. 2017 02; 7(2):188-201. Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, Grasso CS, Hugo W, Sandoval S, Torrejon DY, Palaskas N, Rodriguez GA, Parisi G, Azhdam A, Chmielowski B, Cherry G, Seja E, Berent-Maoz B, Shintaku IP, Le DT, Pardoll DM, Diaz LA, Tumeh PC, Graeber TG, Lo RS, Comin-Anduix B, Ribas A. PMID: 27903500.
      View in: PubMed   Mentions: 205     Fields:    Translation:HumansCells
    11. Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma. N Engl J Med. 2016 Sep 01; 375(9):819-29. Zaretsky JM, Garcia-Diaz A, Shin DS, Escuin-Ordinas H, Hugo W, Hu-Lieskovan S, Torrejon DY, Abril-Rodriguez G, Sandoval S, Barthly L, Saco J, Homet Moreno B, Mezzadra R, Chmielowski B, Ruchalski K, Shintaku IP, Sanchez PJ, Puig-Saus C, Cherry G, Seja E, Kong X, Pang J, Berent-Maoz B, Comin-Anduix B, Graeber TG, Tumeh PC, Schumacher TN, Lo RS, Ribas A. PMID: 27433843.
      View in: PubMed   Mentions: 534     Fields:    Translation:HumansCells
    12. Repurposing metformin for cancer treatment: current clinical studies. Oncotarget. 2016 Jun 28; 7(26):40767-40780. Chae YK, Arya A, Malecek MK, Shin DS, Carneiro B, Chandra S, Kaplan J, Kalyan A, Altman JK, Platanias L, Giles F. PMID: 27004404.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    13. Human Epidermal Growth Factor Receptor 2 (HER-2/neu)-Directed Therapy for Rare Metastatic Epithelial Tumors with HER-2 Amplification. Case Rep Oncol. 2016 May-Aug; 9(2):298-304. Shin DS, Sherry T, Kallen ME, Wong S, Drakaki A. PMID: 27403128.
      View in: PubMed   Mentions:
    14. PD-1 Blockade Expands Intratumoral Memory T Cells. Cancer Immunol Res. 2016 Mar; 4(3):194-203. Ribas A, Shin DS, Zaretsky J, Frederiksen J, Cornish A, Avramis E, Seja E, Kivork C, Siebert J, Kaplan-Lefko P, Wang X, Chmielowski B, Glaspy JA, Tumeh PC, Chodon T, Pe'er D, Comin-Anduix B. PMID: 26787823.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCellsCTClinical Trials
    15. Romiplostim mitigates dose-limiting thrombocytopenia of erucic acid for adrenomyeloneuropathy. Br J Haematol. 2015 Dec; 171(5):879-81. Shin DS, Perlman S, Rosove MH. PMID: 25854532.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. The evolution of checkpoint blockade as a cancer therapy: what's here, what's next? Curr Opin Immunol. 2015 Apr; 33:23-35. Shin DS, Ribas A. PMID: 25621841.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    17. Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms. . 2014 Sep; 15(9):991-9. Shin DS, Jordan A, Basu S, Thomas RM, Bandyopadhyay S, de Zoeten EF, Wells AD, Macian F. PMID: 25074018.
      View in: PubMed   Mentions:
    18. Metastatic human epidermal growth factor 2 (HER2/neu) amplified breast cancer with acute fulminant hepatitis responding to trastuzumab, pertuzumab and carboplatin. BMJ Case Rep. 2014 Jun 04; 2014. Macias MN, Shin DS, Ledezma B, Sadeghi S. PMID: 24899001.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method. . 2013 Jun 15; 304(12):C1159-67. Shin DS, Zhao R, Fiser A, Goldman ID. PMID: 23552283.
      View in: PubMed   Mentions:
    20. NFAT1 supports tumor-induced anergy of CD4(+) T cells. Cancer Res. 2012 Sep 15; 72(18):4642-51. Abe BT, Shin DS, Mocholi E, Macian F. PMID: 22865456.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    21. Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption. . 2012 Oct 15; 303(8):C834-42. Shin DS, Zhao R, Fiser A, Goldman DI. PMID: 22843796.
      View in: PubMed   Mentions:
    22. Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1). . 2012 Sep 15; 303(6):C673-81. Zhao R, Shin DS, Fiser A, Goldman ID. PMID: 22785121.
      View in: PubMed   Mentions:
    23. A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding. . 2012 May 01; 302(9):C1405-12. Shin DS, Zhao R, Yap EH, Fiser A, Goldman ID. PMID: 22345511.
      View in: PubMed   Mentions:
    24. Random mutagenesis of the proton-coupled folate transporter (SLC46A1), clustering of mutations, and the bases for associated losses of function. J Biol Chem. 2011 Jul 08; 286(27):24150-8. Zhao R, Shin DS, Diop-Bove N, Ovits CG, Goldman ID. PMID: 21602279.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    25. Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption. Mol Genet Metab. 2011 May; 103(1):33-7. Shin DS, Mahadeo K, Min SH, Diop-Bove N, Clayton P, Zhao R, Goldman ID. PMID: 21333572.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    26. Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method. Biochim Biophys Acta. 2011 Apr; 1808(4):1140-5. Zhao R, Shin DS, Goldman ID. PMID: 21256110.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor response. Cancer Res. 2010 Dec 15; 70(24):10121-30. Cho HM, Rosenblatt JD, Tolba K, Shin SJ, Shin DS, Calfa C, Zhang Y, Shin SU. PMID: 21159634.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption. Blood. 2010 Dec 09; 116(24):5162-9. Shin DS, Min SH, Russell L, Zhao R, Fiser A, Goldman ID. PMID: 20805364.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    29. Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method. Biochemistry. 2010 Apr 06; 49(13):2925-31. Zhao R, Unal ES, Shin DS, Goldman ID. PMID: 20225891.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    30. Use of the T-SPOT.TB assay to detect latent tuberculosis infection among rheumatic disease patients on immunosuppressive therapy. J Rheumatol. 2009 Mar; 36(3):546-51. Behar SM, Shin DS, Maier A, Coblyn J, Helfgott S, Weinblatt ME. PMID: 19228655.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    31. Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death. J Exp Med. 2008 Nov 24; 205(12):2791-801. Chen M, Divangahi M, Gan H, Shin DS, Hong S, Lee DM, Serhan CN, Behar SM, Remold HG. PMID: 18955568.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    32. Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infection. Infect Immun. 2008 May; 76(5):2249-55. Wu Y, Woodworth JS, Shin DS, Morris S, Behar SM. PMID: 18332205.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    33. An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10706-11. Ng PP, Dela Cruz JS, Sorour DN, Stinebaugh JM, Shin SU, Shin DS, Morrison SL, Penichet ML. PMID: 12149472.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
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